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Biomechanical Weight-Bearing Prescription for Tibia diaphysis | ComeBack Mobility Case Study Description: In this case study, ComeBack Mobility presents a personalized biomechanical analysis for a 34-year-old Female patient with a Tibia diaphysis (AO Classification: 42-C3). 42-C3 — Complex Femoral Shaft Fracture 42 — fracture of the femoral diaphysis (shaft) C — complex fracture type (segmental or multi-fragmentary with no direct cortical contact between main fragments) 3 — complex, irregular fracture pattern with multiple fragments Anatomical Location: The fracture involves the diaphyseal region of the femur — the long, central portion of the thigh bone between the proximal and distal metaphyses. Fracture Pattern: This is a highly comminuted, multi-fragmentary fracture of the femoral shaft. The bone is broken into several fragments with no stable cortical contact between the main proximal and distal segments. The fracture lines are irregular and may create segmental bone fragments, resulting in significant instability. Using 3D segmentation of the bone fragments, fixator components, and fracture gap, we created a detailed finite element model to assess healing parameters. Based on the analysis of: • Fracture gap movement (mm) • Percentage of voxels in the Claes Healing Window • Fixation safety factor — we determined that the optimal weight-bearing range for this patient is 25%–45% of body weight. This range provides the best balance between stimulation for healing and structural safety, helping avoid complications such as delayed union or fixation failure.