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#how_to_replace_cornea_for_vision_for_others #Doctor_Dipak_Nag #cornea #vision #replace_cornea #improvevision #improve_vision_without_surgery #cornea_transplant #surgery #transplant #allogenic #anatomy #cornea #extra_care #blind #organ #desease #doctor #orbitalsculpting #retina #এক্সট্রা_কেয়ার #extracare I'll be discussing how to replace cornia for vision for others. If you are looking for a way to improve the vision without surgery, then you may want to consider replacing cornea with a new technique called orbital sculpting. In this video, I'll discuss the benefits and possible risks of this surgery, and an overview of the procedure. Corneal blindness is one of the major causes of reversible blindness, which can be managed with transplantation of a healthy donor cornea. It is the most successful organ transplantation in the human body as cornea is devoid of vasculature, minimizing the risk of graft rejection. The first successful transplant was performed by Zirm, and since then, corneal transplantation has seen significant evolution. It has been possible because of the relentless efforts by researchers and the increase in knowledge about corneal anatomy, improvement in instruments and advancements in technology. Keratoplasty has come a long way since the initial surgeries where in the whole cornea was replaced to the present day where only the selective diseased layer can be replaced. These newer procedures maintain structural integrity and avoid catastrophic complications associated with open globe surgery. This procedures are broadly classified as full-thickness penetrating keratoplasty and partial lamellar corneal surgeries which include anterior lamellar keratoplasty [sperficial anterior lamellar keratoplasty (SALK), automated lamellar therapeutic keratoplasty (ALTK) and deep anterior lamellar keratoplasty (DALK)] and posterior lamellar keratoplasty [Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK)] broadly. Corneal transplantation or keratoplasty is the most commonly performed and also the most successful allogenic transplant worldwide. Zirm1 performed the first corneal transplantation in 1905. Since then, corneal transplantation has evolved from the replacement of full-thickness cornea to the replacement of selective diseased layers of the cornea. This has been possible because of the improvement in understanding of corneal anatomy, advanced surgical techniques, instruments and microscopes. Organ transplantation is a complex process with multiple legal, ethical and cultural issues. The corneal tissue has several characteristics that make storage and transplantation easier and the eye bank plays an important role in the whole process of corneal retrieval, storage and transplantation. The cornea is a transparent and avascular structure of the eye, which constitutes the anterior-most part of the eyeball. It consists of six different anatomical layers (Fig. 1). The anterior-most is epithelium consisting of squamous cells, wing cells and basal cells. The second layer is Bowman's membrane, which has regenerative properties. Stroma constitutes the major part of the cornea and contains keratocytes and collagen lamellae that are densely distributed in the anterior as compared to the posterior stroma. Dua's layer is almost 10-15 μm in thickness and remains strongly adhered to overlying stromal fibres. The Descemet membrane provides a base for endothelial cells that have a key role in maintaining corneal transparency. In 1813 Himly first mentioned the concept of corneal transplantation, but Von Hippel actually performed the first transplant in 1886 by replacing human diseased cornea with that of rabbit cornea. Fuchs did the first lamellar keratoplasty (LK), which was not accepted well because of poor outcomes in terms of visual quality. The first successful corneal transplant was performed by Zirm in 1905. Keratoplasty can be done for various purposes and is classified as therapeutic, tectonic and optical. Therapeutic keratoplasty is done to remove the infective portion of the cornea mainly in cases of recalcitrant or perforated infective keratitis. Tectonic keratoplasty provides support and maintains the integrity of the globe. Optical keratoplasty aims to restore vision and has seen various advancements with time that has led to refinement in post-operative visual quality and outcomes. In the 19th century, LK that involves removal of selective corneal layers was initially used to treat anterior corneal opacities. It was used to treat corneal scars, keratoconus but discontinued due to suboptimal visual gain, which could be attributed to irregular interface or residual opacities6. It was also associated with a longer learning curve. This led to an increase in the popularity of full-thickness penetrating keratoplasty (PKP). যুক্ত থাকুন আমাদের ফেসবুক পেজে - / extracare351 #Extra_Care @extracare