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⭐️Subscribe Doctor Why on Telegram - https://t.me/doctorwhymed_bot (press start, and choose your plan) Fetal fibronectin is an extracellular matrix protein acting like "glue" at the maternal-fetal interface (chorio-decidual junction). Its presence in cervicovaginal secretions between 22 and 34 weeks suggests disruption of this interface and an increased risk of impending preterm delivery. Clinical Importance: While its positive predictive value is modest, a negative fFN test is highly reassuring. In women with symptoms of PTL but minimal cervical change, a negative fFN strongly indicates that delivery within the next 7-14 days is unlikely. This helps clinicians avoid unnecessary hospital admissions, interventions (like tocolytics or steroids), and patient anxiety.. #pretermlabor #fetal #fibronectin Professor Armen Astvatsatryan, MD, PhD, ScD, Fellow of European Society of Cardiology. First Dean and Founder of Faculty of Public Health of European Regional Educational Academy (now University). One of 100 Top Health Professionals - 2007 by the International Biographical Center`s (Cambridge, England) [email protected] https://t.me/ugolokdoctora / armenastvatsatryan