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Casual Conversations is made possible by the generosity of our supporters. Your donation helps us keep these conversations going. Please consider giving today: https://www.cannaspecialists.org/donate In this episode, John Malanca from the Association of Cannabinoids Specialist leads a discussion with Dr. Jordan Tishler, Dr. Adam Abodeely, and Dr. Sandra Carrillo about synthetic cannabinoids, including Marinol, K2, Spice, and various Delta compounds. They cover the history and use of Marinol in treating pain, mood disorders, and appetite issues, particularly during the AIDS crisis and for cancer patients. Dr. Abodeely and Dr. Carrillo share their clinical experiences with Marinol, noting its side effects and the comparative benefits of whole-plant cannabis extracts. Dr. Tishler discusses the chemical differences between synthetic and plant-based THC, highlighting varying efficacy and safety concerns. The discussion also touches on synthetic cannabinoids in the pharmaceutical industry, the potential risks of illegal synthetic products targeting youth, and the need for more education. The episode concludes with practical advice on the usage of Marinol in hospitals and the potential for legal changes to improve access to cannabis-based therapies.