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Reference: https://www.videogie.org/article/S246... Endoscopic hemostasis is a critical intervention for managing diverticular hemorrhage, particularly in patients with a colonic conduit. This technique involves the use of specialized tools to achieve hemostasis, thereby preventing further blood loss and complications. One innovative approach to this procedure is the application of an over-the-scope clip, which provides a robust mechanism for securing the bleeding site. The over-the-scope clip is designed to be deployed over the endoscope, allowing for precise placement and effective closure of the diverticular defect, which is often challenging due to the anatomical complexities of the colonic conduit. The procedure begins with careful endoscopic evaluation to identify the source of the hemorrhage. Once the bleeding diverticulum is located, the endoscopist can maneuver the over-the-scope clip into position. This clip is advantageous because it can grasp and compress the tissue, promoting hemostasis through mechanical closure. The ability to apply significant force without damaging surrounding structures is a key benefit of this technique, making it particularly suitable for diverticular bleeding, where the tissue may be fragile and prone to further injury. Following the application of the over-the-scope clip, continuous monitoring and follow-up are essential to ensure that hemostasis is maintained and to assess for any potential complications. The effectiveness of this method has been supported by various studies, which highlight its success rate in achieving hemostasis in diverticular hemorrhage cases. As endoscopic techniques continue to evolve, the use of over-the-scope clips represents a significant advancement in the management of gastrointestinal bleeding, offering a minimally invasive option that can lead to improved patient outcomes and reduced need for surgical intervention.