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Vishal Patel, MD, FAAD, FACMS, The George Washington School of Medicine and Health Sciences, Washington, DC, provides an overview of Moh’s surgery, a surgical technique for skin cancer resection, particularly basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs), that allows the surgeon to evaluate the complete circumferential and deep surgical margin. More recently, the use of Mohs surgery has been extended beyond treating the skin cancers it was developed for, with a growing body of evidence supporting its use in more aggressing tumors such as melanoma and Merkel cell carcinoma. This interview took place at the 18th World Congress on Cancers of the Skin (WCCS 2022) in Buenos Aires, Argentina. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.