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What is Anzupgo (Delgocitinib)? What is Anzupgo used for? Discover how Anzupgo cream helps manage chronic hand eczema with a steroid-free approach. Learn about application, benefits, and safety tips! Comment and share your experience. Suffering from chronic hand eczema? Discover a new, targeted hand eczema treatment option for managing this challenging skin condition. Learn about the benefits, risks, and proper usage to find dry skin relief. Get the latest dermatology insights about how to heal eczema naturally! Introduction to Chronic Hand Eczema Overview and Impact: Chronic hand eczema is a long-lasting inflammatory skin condition primarily affecting the hands, characterized by symptoms such as redness, intense itching, pain, dryness, skin cracking, scaling, and thickening. The condition significantly impacts daily life and is defined as chronic if it persists for three months or recurs at least twice yearly. Challenges in Management: Many patients struggle to manage symptoms, particularly when standard treatments like topical corticosteroids are ineffective or contraindicated. Anzupgo (Delgocitinib) Cream Overview Treatment Option: Anzupgo (Delgocitinib Cream) is a newly available, prescription, steroid-free topical medication specifically for adults with moderate to severe chronic hand eczema. It is particularly beneficial for those who have not responded adequately to corticosteroids or cannot use them, thereby broadening therapeutic options. Mechanism of Action: Belonging to the Janus kinase (JAK) inhibitor class, its active ingredient, Delgocitinib, targets enzymes responsible for inflammation in chronic hand eczema. By inhibiting JAK activity, it effectively reduces inflammation and alleviates symptoms. Proper Use and Safety Guidelines Application Instructions: The cream should be applied in a thin layer twice daily to clean, dry skin on affected hands and wrists. Users must avoid contact with mucous membranes and adhere to prescribed dosage limits (no more than 30 grams in two weeks or 60 grams in a month). Precautionary Measures: After application, hands should be washed if the cream is applied to someone else. Proper storage at room temperature (20–25°C / 68–77°F) and keeping the medication out of reach of children and pets are recommended. Potential Side Effects and Monitoring Common Side Effects: Most side effects are mild and localized, such as pain, tingling, itching, or redness at the application site. Some patients may experience bacterial infections like cellulitis or nail infections, or decreased white blood cell counts. Serious Risks and Monitoring: As a JAK inhibitor, Anzupgo may weaken the immune system, increasing the risk of serious infections (e.g., TB, shingles, herpes zoster, eczema herpeticum). Patients need regular health monitoring, and immediate medical attention is necessary if any infection symptoms occur. Special Considerations and Contraindications Infection and Cancer Risks: Use is contraindicated in patients with active or serious infections. Long-term use may increase the risk of non-melanoma skin cancers, so regular skin checks and minimizing sun exposure using sunscreen and protective clothing are advised. Systemic Risks and Drug Interactions: While topical, other JAK inhibitors have systemic risks (e.g., increased mortality in high-risk individuals). Use with other JAK inhibitors or potent immunosuppressants is not recommended. Full disclosure of all medications, including over-the-counter and herbal supplements, is essential to avoid harmful interactions. Use in Pregnancy, Breastfeeding, and Vaccinations Pregnancy and Breastfeeding: The safety of Anzupgo during pregnancy and breastfeeding is unknown. Consult a healthcare provider to assess risks versus benefits and discuss the best approach to feeding if breastfeeding. Vaccinations: Live vaccines should be avoided immediately before, during, or after treatment. Vaccination history and plans should be communicated to the prescribing healthcare provider. Conclusion: Importance of Professional Guidance Informed Decision-Making: Before initiating Anzupgo, a thorough consultation with a healthcare provider is crucial. This ensures the treatment is appropriate based on individual health needs and risks. 00:00 Understanding Hand Eczema 01:05 About Anzupgo 02:55 Side Effects & Safety 05:21 Special Precautions 07:10 Key Ingredients 07:52 Final Advice #anzupgo #chronichandeczema #delgocitinib #eczematreatment #fdaapprovesanzupgo #anzupgocream #chronichandeczematreatment #eczemacream #handeczema #eczematreatmentsuccess #delgocitinibcream #handeczemasymptoms #handeczemamanagement #handeczemacream #handeczematreatment #topicalskintreatment #howtotreathandeczema #whatisanzupgo #whatisanzupgousedfor #anzupgofdaapproval #anzupgosideeffects