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The average woman has a one-in-eight chance of developing breast cancer over the course of her lifetime. There's always concern about the cancer coming back. Scientists at UW Medicine in Seattle have been developing a new vaccine to try to stop such recurrences. As part of their studies, the lab identified autoantibodies against several breast cancer stem cell proteins that show up in the blood of women with advanced breast cancer. And that’s the research to be discussed at an ASCO poster presentation. “We can look at the patient’s blood and tell just from that whether the patient is in more advances stages of breast cancer versus less advanced stages,” Dr. Sasha Stanton said. “We’re studying whether these antibodies are markers of aggression and possibly markers of progression of the cancer.” The autoantibodies are the body’s response to try to battle the cancer. After the poster presentation, Stanton and colleagues will continue to analyze whether a blood test for these autoantibodies might give medical providers a head start in identifying cancer in someone to provide earlier treatment. “The autoantibody response can be detected with just a small amount of the disease. I would hope that we ultimately could produce a biomarker so that we could tell someone who has been completely treated with breast cancer whether or not she’s at risk of recurrence sooner than we can right now through imaging and other tests," Stanton said. For the media: To interview Dr. Stanton, please contact please contact Walter Neary at [email protected] or 253-389-0736. For more stories from the UW Medicine Newsroom, check out https://newsroom.uw.edu/.