Master Genetics & Pedigree Analysis скачать в хорошем качестве

Master Genetics & Pedigree Analysis

Do you freeze up when you see a pedigree chart in an exam? 🥶 Most students do. They guess, and they lose marks. Today, that ends. In this video, Dr. P gives you the exact blueprint to solve any pedigree analysis question with 100% confidence. While this video covers the essential theory from Robbins Genetics, the focus is on practical application. We teach you the "Knight's Move" for X-linked recessive, the "Male-to-Male" dealbreaker rule, and the "Maternal Waterfall" of mitochondrial inheritance. The video provides a comprehensive guide to understanding genetics and pedigree analysis. Here's a breakdown of the topics covered: Introduction to Genetics (0:07-1:02): Dr. P introduces the topic of genetics, emphasizing that it's based on math and logic, and promises to help viewers solve pedigree charts quickly. Vocabulary of Genetics (1:02-3:05): This section defines fundamental genetic terms like penetrance vs. expressivity and pleiotropy vs. genetic heterogeneity, along with examples. Mutations (3:07-3:51): The video explains different types of mutations, including point mutations, frameshift mutations, and trinucleotide repeats, using analogies to make them understandable. How to Draw a Pedigree Chart (4:00-6:47): A step-by-step guide on drawing pedigree charts, covering symbols for individuals, connections for relationships, and status indicators for affected or carrier individuals. Mendelian Inheritance: The Big Four (6:53-10:07): This segment details autosomal dominant, autosomal recessive, X-linked recessive, and X-linked dominant inheritance patterns, explaining their characteristics and providing examples. Dr. P's Sequential Pedigree Protocol (10:10-13:13): A five-step algorithm for analyzing any pedigree chart to determine the inheritance pattern. Case Studies: Hemophilia A and Marfan Syndrome (13:19-16:44): Practical application of the pedigree analysis protocol through two clinical scenarios. Non-Mendelian Disorders: The Rebels (16:46-25:21): This part covers more complex inheritance patterns that don't follow standard Mendelian rules, including trinucleotide repeat mutations (17:28), mitochondrial inheritance (19:34), and genomic imprinting (20:52). Cytogenetics: The Study of Chromosomes (25:51-31:27): An overview of chromosomal structures, numerical and structural abnormalities, and sex chromosome disorders. Genetic Diagnostic Techniques (Toolkit) (31:29-35:05): This section discusses various diagnostic tools like karyotyping, FISH, chromosomal microarray, and PCR, explaining when and why to use each. By the end of this masterclass, you will know: The exact 5 questions to ask every pedigree chart. How to instantly differentiate AD, AR, XLR, XLD, and Mitochondrial patterns. The difference between structural protein defects vs. enzyme defects. High-yield mnemonics for remembering key diseases for NEET PG. Don't just watch—grab a pen and practice along with us! 📄 Grab the "FREE GENETICS Cheat Sheet" PDF below! [https://drive.google.com/drive/folder...] Join the Conquer Pathology community and turn your weakest topic into your strongest. Hit subscribe!