Retroperitoneal fibrosis RPF excessive fibrous tissue growth in the retroperitoneal space скачать в хорошем качестве

Retroperitoneal fibrosis RPF excessive fibrous tissue growth in the retroperitoneal space

Retroperitoneal fibrosis (RPF), also known as Ormond's disease, is a rare condition characterized by the excessive growth of fibrous tissue in the retroperitoneal space, which is located behind the stomach and intestines. This fibrous tissue can compress structures like the ureters, leading to complications such as ureteral obstruction and kidney damage2. Key Features: Symptoms: Patients may experience abdominal or back pain, reduced urine output, leg swelling, and systemic symptoms like fever or weight loss. Causes: While the exact cause is unknown in many cases, RPF can be linked to autoimmune conditions (e.g., IgG4-related disease), infections, malignancies, certain medications, and exposure to asbestos3. Diagnosis: Imaging techniques like CT or MRI are crucial for identifying the fibrous mass and assessing its impact on surrounding structures. Treatment: Management often involves corticosteroids to reduce inflammation, immunosuppressive drugs, and surgical interventions to relieve ureteral obstruction #Fibrosis