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Opioid tolerance, dependence and addiction are all manifestations of brain and central nervous system changes resulting from chronic opioid use. In this video, I’ll let you know how opioids affect brain processes to produce tolerance, dependence and withdrawal, so you can educate your patients more confidently around these topics, and support them in their decision to begin an opioid reduction. USEFUL LINKS RELATED TO THIS VIDEO: The Neurobiology of Opioid Dependence: Implications for Treatment (Research Paper) - https://www.ncbi.nlm.nih.gov/pmc/arti... Why Opioids for Chronic Pain DON'T WORK - • Why Opioids for Chronic Pain DON'T WORK MY FREE EMAIL COURSE: 🚀 Forming Healthy Habits & Achieving Your Goals - https://thewellnesspuzzle.ck.page/8fc... 💌 My Newsletter - https://thewellnesspuzzle.ck.page/dd0... 🌍 My Blog and Website - https://thewellnesspuzzle.com/ 📷 My Instagram - / _thewellnesspuzzle 🐦 My Twitter - / mahinkohli 👥 My Facebook - / thewellnesspuzzle 🎵 My TikTok - / thewellnesspuzzle WHO AM I: I'm Mahin, an Advanced Practice Physiotherapist and Independent Prescriber specialising in Pain Management, working in the West Midlands, UK. I started The Wellness Puzzle to help people live a life full of enjoyment and experiences, with the freedom of knowing their health or pain will not be a barrier, in the same way I have helped many of my patients. Outside of work as a Physio and The Wellness Puzzle, I love travelling, coffee, cricket, creating new experiences with the people close to me and keeping active. Thanks for watching and following my channel! 00:00 Intro 00:37 Dependence vs Addiction 01:48 Opioids Produce Pleasure 03:08 Opioid Tolerance, Dependence & Withdrawal NOTE: Some of the links in this description may be affiliate links. Purchasing from such links helps me keep The Wellness Puzzle sustainable and create valuable content for you every week – thank you for your support! DISCLAIMER: The Wellness Puzzle is intended for educational and reference purposes only. The videos on my channel, content on my website or on social media are not intended to be a substitute for professional advice, diagnosis or treatment by a healthcare or medical professional. You should always carry out your own research and seek medical advice where required regarding a medical condition. Never disregard professional advice or delay in seeking such advice because of something you have heard on this video or read on my blog or website.