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Mayo Clinic cardiac surgeon Joseph Dearani, M.D., discusses thoracic aortic aneurysms and syndromes in children. Common syndromes relating to thoracic aortic aneurysms include Marfan, Loeys-Diets, Ehlers-Danlos, as well as surgical treatment options. Visit http://www.mayoclinic.org/diseases-co... for more information on thoracic aortic aneurysms and syndromes in children at Mayo Clinic. Thoracic aortic aneurysm in children is usually associated with some type of connective tissue disorder. Some of these connective tissue disorders include Marfan syndrome, Loeys-Dietz syndrome, and Ehlers-Danlos syndrome. Other features associated with aortic aneurysms are eye and skeletal abnormalities, pectus deformity, hypertelorism, bifid uvula, and tortuosity. Mayo Clinic has a comprehensive aortic clinic for children and adults that offers a multidisciplinary approach to medical and surgical treatment options. Some of the surgical options include aortic root surgery, valve-sparing aortic root replacement, and the Bentall procedure. Timing of surgery is essential for the optimization of outcomes.