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SA Node Dysfunction (Sick Sinus Syndrome) explained in a clear, structured, and simplified way — based on Harrison’s Principles of Internal Medicine (22nd Edition). This video covers the full clinical understanding of disorders affecting the heart’s natural pacemaker, focusing on mechanisms, diagnosis, and management. 🔍 Topics covered: 0:00 – Introduction to SA Node Dysfunction Understanding the heart’s natural pacemaker and why a slow heart rate does not automatically mean a pacemaker is needed. 1:40 – Anatomy & Function of the SA Node Location, cellular structure, and heterogeneous nature of the SA node. 4:49 – Aging & Heart Rate How aging affects intrinsic heart rate and physiologic compensation. 5:25 – Definition of SA Node Dysfunction (SND) When the SA node becomes unreliable in generating or conducting impulses. 6:08 – Impulse Formation Disorders • Sinus bradycardia • Sinus arrest • Chronotropic incompetence 9:10 – Impulse Conduction Disorders (SA Exit Block) • Type I • Type II • Type III Mechanism and ECG patterns. 13:17 – Tachy-Brady Syndrome Alternating fast and slow rhythms, the medication paradox, and management challenges. 17:32 – Causes of SND: Intrinsic Factors Aging, fibrosis, ischemia, structural heart disease, infiltrative diseases. 20:07 Causes of SND: Extrinsic Factors Medications, hypothyroidism, Lyme disease, sleep apnea, increased vagal tone, carotid sinus hypersensitivity. 27:44 – Clinical Presentation Dizziness, syncope, fatigue, exercise intolerance. 28:14 - Diagnostic Tools • ECG • Holter monitoring • Wearables / smartwatches • Invasive electrophysiology Importance of symptom–rhythm correlation. 33:25 – Management Approach & Pacemaker Indications Stepwise evaluation, reversible causes, and pacing decisions based on symptoms. 35:54 – Pacemaker Technology & Types • NBG code explained • Rate-responsive pacing • Single vs dual chamber devices • Complications • Leadless pacemakers 🎯 Designed for medical students, residents, and exam preparation, with a focus on clinical reasoning and real-world application. PDF SLIDES https://drive.google.com/file/d/1780L...