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Surgical Advances in Melanoma

In this presentation, Dr. Neuman walks through modern approaches to managing melanoma, from diagnosis to treatment. Using a case-based discussion, this talk highlights advances in surgical management, sentinel lymph node evaluation, and integration and recurrent melanoma. Key topics covered include: Primary Treatment of Melanoma: Understanding wide local excision and current margin recommendations for intermediate-thickness melanomas, including ongoing trials like Melmar 2 evaluating 1 cm versus 2 cm margins. Sentinel Lymph Node Biopsy (SLNB): How SLNB guides prognosis, imaging, and systemic therapy decisions, and updates from the MSLT2 trial on active surveillance versus completion lymph node dissection. Neoadjuvant Immunotherapy: The rationale for giving immunotherapy before surgery, recent clinical trial outcomes, and how it can improve long-term outcomes. Multidisciplinary Care: Combining surgical approaches with systemic therapies to optimize survival while minimizing treatment morbidity. Case-Based Learning: A 55-year-old patient case illustrating real-world decision-making and sequencing of surgery and immunotherapy. Dr. Neuman emphasizes the importance of integrating surgical expertise with systemic therapy innovations to provide the best outcomes for melanoma patients, reflecting how research and clinical advances are reshaping treatment strategies.