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VDOS 2024: The 13th International Workshop on Vaccine and Drug Ontology Studies. Workshop Website (Virtual) https://vdos-workshop.github.io/vdos2... Presented by Mr. Anthony Huffma, University of Michigan. Abstract: "Background: There have been a large amount of vaccine studies getting published; however, it is often difficult to integrate these studies due to a big data disintegration issue. Results: We first developed a Vaccine Study Minimal Information Standard (VS-MIS), and then used the Vaccine Ontology (VO) and Vaccine Investigation Ontology (VIO) to represent the minimal information standard. VS-MIS utilizes the Investigation/Study/Assay (ISA) format to represent two major types of vaccine studies, host response to vaccines and pathogen challenge study outcomes. We have expanded on the 36 metadata entries used in ISA to include 43 different variables utilized in vaccine studies and added 70+ new terms to VO. Furthermore, we have developed two use cases to apply the VS-MIS and VIO ontological representation. Conclusion: The VS-MIS and its associated ontology representation and demonstrations show its potential for improving vaccine study representation and integration. "