Visualization of the epidermal homeostasis: the normal epidermis скачать в хорошем качестве

Visualization of the epidermal homeostasis: the normal epidermis

This playlist accompanies the research article of Zhang et al. “Modeling the Epidermis Homeostasis and the Psoriasis” http://rsif.royalsocietypublishing.or..., and provides videos of the epidermis stratification under normal and pathological (psoriasis) conditions. The videos visualize dynamics of epidermis homeostasis generated by simulations with an agent-based cell migration model of a two-dimensional (cross-sectional) volume. Cellular events from stochastic simulation of the population kinetics are incorporated into the cell migration model to visualize the renewal process. The video visualizes an area of 1 mm width and 10 μm thickness to contain a two-dimensional sheet of cells. The simulation starts with an initial stem cell population of 10. To show simulation details, ranges of fast dynamics such as in the early transient phase population growth need high-density sampling (1 snapshot per day), whereas ranges of slow dynamics such as the steady state only require low-density sampling (1 snapshot per 4 days).