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Systemic Lupus Erythematosus (SLE) is a chronic autoimmune connective tissue disorder characterized by the production of autoantibodies against nuclear components, leading to multisystem inflammation and organ damage. It commonly affects young women and follows a relapsing–remitting course. In this video, SLE is explained in a simple, clinical, and exam-oriented manner, covering: • Definition and overview of SLE • Pathogenesis and immunological basis • Clinical features involving skin, joints, kidneys, nervous system, and hematological system • Important investigations including ANA, anti-dsDNA, anti-Sm antibodies, and complement levels • Management approach including hydroxychloroquine, corticosteroids, and immunosuppressive therapy • High-yield exam and viva points for MBBS, NEET PG, NEXT, and FMGE This video is intended for MBBS students, interns, and postgraduate aspirants to build a clear conceptual and clinical understanding of SLE. _______ SLE #SystemicLupusErythematosus #Lupus #AutoimmuneDisease #Rheumatology #Immunology #Medicine #InternalMedicine #ClinicalMedicine #LupusNephritis #Autoantibodies #ANA #AntiDsDNA #ConnectiveTissueDisease #MBBS #MBBSLife #NEETPG #NEETPGPrep #NEXTExam #FMGE #MedicalStudents #MedicalEducation #MedicoLife #DoctorLife #IndianMedicos #MedicosOfIndia #MedicineExplained #MedicalYouTube #MedicalReels #DoctorReels #LearnMedicine #StudyMedicine #ExamOriented #VivaPreparation #MedicalViral #EducationViral #Trending #Viral #ForYou #FYP #explorepage _______ Follow BrainlessMedico for Medicine made simple and exam ready.