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Description: Myelofibrosis (MF) is one of the more rare forms of myeloproliferative neoplasms (MPNs) but also the most common one to turn into acute myeloid leukemia (AML). That’s why so much research is pouring into more treatment options for MF, with clinical trials trying to test new drugs, as well as combinations. Historically speaking, MF treatments often become an option for patients of other MPNs, like polycthemia vera (PV) and essential thrombocythemia (ET). To help sort through what patients need to know, we sit down with top MPNs specialist, Dr. Ruben Mesa. Featuring: Dr. Ruben Mesa Executive Director of Mays Cancer Center Director of UT Health San Antonio MD Anderson Cancer Center Myeloproliferative Neoplasms (MPNs) Specialist In this Series: Dr. Mesa covers the latest updates focused on MPNs following the biggest blood cancer/disease conference (ASH) held at the end of 2021 that looked forward to emerging treatments studied in 2022 and beyond. Full story & transcript → Updated Soon at www.ThePatientStory.com Videos: 1) Essential Thrombocythemia Updates for Patients and Caregivers (2022): • Essential Thrombocythemia: What Patie... 2) Polycythemia Vera: Latest Updates for Patients & Caregivers in 2022: • Polycythemia Vera: Latest Updates for... The interview has only been edited for clarity. Join Our Community: Website : https://www.thepatientstory.com/ Facebook: @ThePatientStory Instagram: @ThePatientStory Twitter: @patient_story Contents of this video: 00:00 - intro 00:17 - Biggest updates on myelofibrosis and treatments 07:03 - Deciding if patients should start with single drug or combination 08:35 - What are the known side effects of pelebresib? 09:46 - Pacritinib's impact on patients with more severe low platelets 10:47 - Overall look at MPN treatments in 2022 12:34 - Expected update for why MF progresses into AML (acute myeloid leukemia) 13:54 - The goal of curing patients with MPNs 15:20 - The importance of clinical trials for patients 16:53 -Community oncologists working with MPN specialists ____________________________ #ThePatientStory #bloodcancer #blooddisease #hematology #oncology #MPN #myeloproliferativeneoplasms #essentialthrombocythemia #polycythemiavera #clinicaltrials #relapsedrefractory #Patientcare #cancertreatment #Cartcelltherapy