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Andrew Pask is Chief Biology Officer at Colossal Biosciences and a professor of genetics at the University of Melbourne. He’s spent over 30 years on the front lines of marsupial conservation and now leads one of the most ambitious projects in biology: the genetic resurrection and rewilding of the extinct Tasmanian tiger. Sponsors: Get 1 Month Free of ConsensusAi: https://get.consensus.app/we00d2cmjpqe Mind Labs Pro Scientifically Rigorous Supplements: https://www.mindlabpro.com/?a_aid=67f... De-extinction isn’t science fiction anymore — it’s a toolkit for saving what’s left of the natural world. From woolly mammoths to dodos to genetically edited quolls, Andrew’s work sits at the crossroads of synthetic biology, ecological restoration, and moral philosophy. Expect to learn why de-extinction might be the only way to preserve biodiversity, how CRISPR and ancient DNA are being used to rebuild lost genomes, what species we can and should bring back, the cultural myths and ethical fears surrounding “playing God,” the truth about the dire wolf announcement, why apex predators matter more than you think, how genetically reprogrammed animals might rescue ecosystems, what Jurassic Park got right — and what it absolutely didn’t, and much more... Timestamps: 00:00 The Mission of De-Extinction 03:03 Genomic Advances in De-Extinction 05:52 The Process of Rebuilding Extinct Species 08:53 Conservation and Genetic Diversity 12:04 Targeting Endangered Species 14:48 Rewilding the Tasmanian Tiger 18:06 Monitoring and Managing Ecosystems 29:23 The Complexity of Ecosystems and Species Interactions 32:01 Genetic Diversity and Its Importance 38:12 The Role of Genetic Diversity in Climate Resilience 40:51 The Urgency of De-Extinction Technology 43:19 The Future of Tasmanian Tigers and Rewilding 45:39 Woolly Mammoths: Ecosystem Engineers 50:09 Funding and Ethical Considerations in De-Extinction 53:42 The Moral Obligation of De-Extinction 56:42 Navigating the Controversy of Species Classification 01:01:04 The Role of Marketing in Conservation 01:04:38 Defining Ethical Boundaries in Genetic Engineering 01:10:30 Policy Challenges in Genetic Conservation 01:14:06 Future Projects in De-Extinction ... ❤️ Subscribe to our main channel - / @thegiantsshoulder 💚 Follow on Spotify - https://open.spotify.com/show/5m3Gta5... 💜 Follow on Apple Podcasts - https://podcasts.apple.com/ie/podcast... Download my FREE EBook 26 Neuroscience Books for 2026 HERE: https://thegiantsshoulder.com/