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MATTERHORN Trial 2025: Durvalumab + FLOT—A New Era in Gastric Cancer Treatment | Dr. Gunjan Desai Join Dr. Gunjan Desai, a leading gastrointestinal and hepatopancreaticobiliary surgeon at Lilavati Hospital, Mumbai, as he delves into the groundbreaking findings of the MATTERHORN Phase III trial. This pivotal study has introduced a transformative approach in the management of resectable gastric and gastroesophageal junction (GEJ) adenocarcinoma. Key Highlights: Enhanced Event-Free Survival (EFS): The addition of durvalumab (Imfinzi) to the standard FLOT chemotherapy regimen resulted in a 29% improvement in EFS compared to FLOT alone, marking a significant advancement in treatment efficacy . Robust Clinical Outcomes: Patients receiving the durvalumab-FLOT combination exhibited a two-year EFS rate of 67.4%, surpassing the 58.5% observed with chemotherapy alone . appliedclinicaltrialsonline.com Safety and Surgical Compatibility: The trial reported no new safety concerns, and the integration of durvalumab did not delay surgical interventions, underscoring its feasibility in perioperative settings . onclive.com Global Applicability: Conducted across 20 countries, the MATTERHORN trial's diverse participant base supports the broad adoption of this regimen as a new standard of care . 📌 Stay Informed: For more insights into the evolving landscape of gastric cancer treatment and the implications of the MATTERHORN trial, subscribe to our channel and enable notifications. #MATTERHORNTrial #GastricCancer #Durvalumab #FLOT #OncologyBreakthrough #DrGunjanDesai #LilavatiHospital #CancerResearch #Immunotherapy #ASCO2025 COME JOIN US: OUR DETAILS FACEBOOK: https://bit.ly/3qaO53R TWITTER: https://bit.ly/3legZw7 INSTAGRAM: https://bit.ly/33mAJaK E-MAIL ID: [email protected] WE SUPPORT AND RECOMMEND Freedom of expression, positivity, and meditation: https://rdbl.co/3fQMStK VISIT THE LINK, IF YOU DO TOO. OUR MOST VIEWED SURGERY VIDEOS STEP BY STEP LAPAROSCOPIC CHOLECYSTECTOMY: • Laparoscopic cholecystectomy - Step by ste... CRITICAL VIEW OF SAFETY IN LAP CHOLECYSTECTOMY: • Critical view of safety - What to do when ... So. let's have fun... Do SHARE, SUBSCRIBE, LIKE if you like the approach to this video. Also, LEAVE TOPICS, SUGGESTIONS in the comments. Let's make surgery fun, factual, and free...