Practice final Q2a -Screen for position effect variegation mutants скачать в хорошем качестве

Practice final Q2a -Screen for position effect variegation mutants

You are interested in the commercial silk business but your silk worms (Bombyx mori) appear to be inappropriately silencing genes required for silk formation. You decide that you should look for mutants that suppress silencing. To make your job easier you take advantage of a strain where the white gene, which is essential for the formation of the normal brown eye pigment, has been inserted adjacent to a block of heterochromatin. The resulting moths (what silk worms grow up to be) have a variegated eye phenotype (white and brown patches). You mutagenize your moths and collect F2s with altered eye phenotypes. a) Predict the phenotype of suppressors of the variegated eye phenotype? b) Predict the phenotype of enhancers of the variegated eye phenotype?