Predicting Early Post-Surgical Recurrence in pNETs скачать в хорошем качестве

Predicting Early Post-Surgical Recurrence in pNETs

In an interview with CancerNetwork® at the 2025 North American Neuroendocrine Tumor Society (NANETS) Multidisciplinary Net Medical Symposium, Stefano Partelli, MD, PhD, associate professor in the Department of Pancreatic Surgery at IRCCS Ospedale San Raffaele in Milan, Italy, and Julie Hallet, MD, MSc, FRCSC, associate professor of Surgery at the University of Toronto and surgical oncologist at the Odette Cancer Centre – Sunnybrook Health Sciences Centre, stated that the core mission of initiatives like the Collaborative of sUrgical Teams for NeuroEndocrine Tumors (CUTNETs) is to standardize care and mitigate the high risks associated with these complex operations. To them, the management of pancreatic neuroendocrine tumors (pNETs), particularly those requiring complex surgery, necessitates a specialized, high-intensity model that prioritizes quality, safety, and consensus. Initially, Partelli explained that quality metrics in pNET surgery are fundamentally tied to the experience and volume of the treating center, given the high risk of complications and mortality. Therefore, optimal patient outcomes rely not only on surgical skill but appropriate indications determined by a dedicated multidisciplinary team including surgeons, oncologists, and endocrinologists. According to Hallet, a major objective of this collaborative model is to reduce the significant variation in practice currently observed across centers. By standardizing approaches and sharing data across numerous high-volume institutions, CUTNETs aims to generate robust evidence, which Partelli notes is still a long-term need in this field. For patients with liver-dominant metastatic disease, the aims of debulking surgery must be clearly defined and shared among the multidisciplinary team. These aims may include: • Symptom reduction in patients with functioning tumors. • Improving systemic efficacy by reducing the overall disease burden, which can optimize the performance of systemic agents. • Bridging to liver transplant in highly selected patients who are very young. Ultimately, the collaborative effort strives to find the most balanced, evidence-based approaches for a heterogeneous patient population, ensuring the operational aim aligns with the overall oncologic strategy. For more content, visit cancernetwork.com. #pNETs #NeuroendocrineTumors #OncologySurgery #SurgicalQuality #MultidisciplinaryTeam #CUTNETs #LiverMetastases #DebulkingSurgery #CancerCareStandards #OncologyCollaboration Don't forget to check us out on: YouTube:    / @cancernetwork   X/Twitter: https://x.com/cancernetwrk?lang=en LinkedIn: https://www.linkedin.com/company/canc... Facebook:   / cancer-network-100059801696024   Instagram:   / cancernetwrk