CRSwNP Advances: How Biologics are Transforming Treatment 🔬 скачать в хорошем качестве

CRSwNP Advances: How Biologics are Transforming Treatment 🔬

In recent years, biologics have revolutionised the treatment of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) — delivering outcomes once thought impossible. By targeting the type 2 inflammatory cascade that drives CRSwNP, biologics offer a true paradigm shift in patient care. Most biologics act on key mediators, such as IL-4/IL-13, IL-5, and IgE, directly addressing the root cause of the disease. 📌 Where we stand today: Over the past 5 years, three biologics have been approved and reimbursed in many countries: • Omalizumab • Mepolizumab • Dupilumab These therapies have demonstrated proven efficacy, a strong safety profile, and even superiority over repeat surgery in severe, uncontrolled cases. For patients, this means fewer surgeries. For clinicians, it means more pathways to remission. 🔬 What’s next? Exciting new research is underway. Two major trials recently published highlight the pipeline of novel molecules: • Depemokimab (twice-yearly dosing) — The Lancet https://www.thelancet.com/journals/la... • Tezepelumab in adults with CRSwNP — The New England Journal of Medicine https://www.nejm.org/doi/full/10.1056... The field is moving fast — and biologics are reshaping the future of CRSwNP treatment. To tell us more about these two promising novel molecules for CRSwNP, EUFOREA invited Prof. Joseph Han (Professor in Otorhinolaryngology, Head and Neck Surgery at Eastern Virginia Medical School, USA, Vice Chair of Clinical Affairs and Administration and Chief of the Division of Allergy) and Prof. Jivianne Lee (Associate Professor of Rhinology & Endoscopic Skull Base Surgery, Head and Neck Surgery at the University of California, USA). -------------------------------------------------------------------------------------------------------------------------- 📽 Subscribe to our YouTube Channel for our latest videos on Allergies and Airway Diseases http://bit.ly/3eMvc3E -------------------------------------------------------------------------------------------------------------------------- 📧 Get in touch with the EUFOREA team for any questions http://bit.ly/2OtlIQp -------------------------------------------------------------------------------------------------------------------------- 📌 EUFOREA is an international non-profit organisation aiming to implement optimal patient care for allergies and airway diseases (asthma, chronic rhinosinusitis, rhinitis) and comorbidities through education, research and advocacy. #euforea 📍Follow us on social media Twitter: http://bit.ly/38wrrM7 LinkedIn: http://bit.ly/2OqtWsf Instagram: http://bit.ly/3TGB5jM ​Facebook: http://bit.ly/3cnNyFF Spotify (podcast): https://bit.ly/3yBa2l3