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Presence of breast pain with stress in the brain and worry. Presence of worry and stress and breast pain associated with it. They can be coexisting together. One can be causing one and the other can cause one. So when the patient has got Fibrocystic disease of the breast, patient will have cyclical mastalgia. So that means there is some amount of hormonal imbalance happening the biggest source of hormone balance in the body is brain cells which is called as pituitary gland which is going to influence the cyclical pattern of hormone secretion in the body. So once the hormones are re regulatory secreted will also affect only the breast irregularly which can lead to Fibrocystic disease of the breast, which can lead to mastalgia. So that could be related to stress and worries in the brain leading to breast pain. In the presence of breast pain it can lead to underlying muscular tissue, we call it pectoralis major muscle that can lead to pain in the muscles and spasm in the pectoralis major muscle can cause breast pain, which is consistent and continuous pain which may be associated with neck pain and shoulder pain. So we should evaluate these patients for Vitamin D deficiency. Vitamin D deficiency itself is known to cause lots of deficiencies and irritability and excitability in the brain and depression in the brain itself. So what causes what we have to first know before we find out whether breast pain is coming.