CLEAR & CURES Seminar w/ Dr. Jodi A. Flaws (University of Illinois Urbana-Champaign) October 2, 2025 скачать в хорошем качестве

CLEAR & CURES Seminar w/ Dr. Jodi A. Flaws (University of Illinois Urbana-Champaign) October 2, 2025

The Center for Urban Responses to Environmental Stressors (CURES) and the Superfund Research Center for Leadership in Environmental Awareness and Research (CLEAR) at Wayne State University presents Dr. Jodi A. Flaws, professor of comparative biosciences at the University of Illinois Urbana-Champaign (UIUC). Dr. Flaws seminar is titled "Environmental Endocrine Disruptors and Female Reproductive Aging." ABSTRACT The female reproductive system ages before any other physiological system, making it a most sensitive indicator of aging. Most women experience reproductive senescence around age 51, but many women experience early reproductive aging (early menopause). This is a serious public health problem because early reproductive aging is associated with early onset of infertility and increased risk of several diseases and early death. Despite the profound impact of early reproductive aging on women’s health, little is known about the mechanisms underlying early reproductive aging. This seminar will provide information on the mechanisms underlying early reproductive aging that in turn, could be used for the identification and development of novel targets for the treatment of early reproductive aging. Specifically, this seminar will provide background information on the processes of normal and early female reproductive aging and environmental endocrine disrupting chemicals known as phthalates. The seminar will include data from experimental and epidemiological studies examining the effects of phthalates on female reproductive aging. Specifically, the seminar will include data showing that phthalate exposure accelerates the onset of reproductive senescence in mice and that phthalate exposure is associated with markers of reproductive aging in women. ABOUT THE SPEAKER Jodi A. Flaws is a professor of comparative biosciences at the University of Illinois Urbana-Champaign (UIUC). She received a B.S. from St. Xavier University, a M.S. from Loyola University of Chicago, and a Ph.D. from the University of Arizona. Following postdoctoral training, Dr. Flaws accepted an assistant professor position at the University of Maryland, where she subsequently was promoted to associate professor. In 2006, Dr. Flaws accepted a position as professor of comparative biosciences at UIUC. Dr. Flaws’ research focuses on determining the mechanisms by which environmental chemicals affect the ovary and female reproductive system. Her research is funded by grants from the National Institute of Environmental Health Sciences (NIEHS). She has published more than 300 peer-reviewed papers and currently serves as the secretary for the Society for the Study of Reproduction and as an associate editor for Toxicological Sciences. Dr. Flaws received the Department of Epidemiology and Preventive Medicine, University of Maryland Student Mentoring Award, the Patricia Sokolove Outstanding Mentor Award, the Dr. Gordon and Mrs. Helen Kruger Research Excellence Award, the Pfizer Animal Health Award for Research Excellence, the University Scholar Award, the Women in Toxicology Mentoring Award from the Society of Toxicology, the Society for the Study of Reproduction Trainee Mentor Award, the Lifetime Scientific Achievement Award from the Reproductive and Developmental Specialty Section of the Society of Toxicology, the Kenneth P. DuBois Award from the Midwest Regional Chapter of the Society of Toxicology, the Dr. Erwin Small Teaching Excellence Award, and the Society for the Study of Reproduction Research Award. ABOUT CLEAR CLEAR is funded by the National Institute of Environmental Health Sciences of the National Institutes of Health (NIH) Superfund Research Program (SRP). The center is dedicated to understanding and mitigating adverse birth outcomes and serious developmental health problems that have been associated with urban environmental exposure to volatile organic chemicals or VOCs, a special class of pollutants found in the subsurface of post-industrial cities like Detroit MI. Sadly, Detroit has the highest preterm birth rate in the country (15.2%), and up to 37 of the 67 Superfund sites in Michigan must manage VOC contamination. Watch this video to learn more and subscribe to our channel. Check out our website www.clear.wayne.edu, or follow us on X at www.x.com/CLEARWSU.