Replicating the human airways in vitro – from normal physiology to disease models for drug testing. скачать в хорошем качестве

Replicating the human airways in vitro – from normal physiology to disease models for drug testing.

Dr. Lindsay Marshall, Humane Society of the United States Talk Title: “Replicating the human airways in vitro – from normal physiology to disease models for drug testing.”  Dr. Marshall completed her Ph.D. in cell biology and protein biochemistry at Dundee Medical School in Scotland.  Her post-doctoral studies at the Department of Medical Specialties, Southampton University, and then the School of Pharmacy and Biomedical Sciences at Portsmouth University investigated the inflammatory responses, repair processes, and innate immunity of the human airways. Her research throughout her academic career at Aston University in Birmingham, UK, where she was a Senior Lecturer in Immunology, continued the theme of human respiratory defenses with the development of multi-cellular, in vitro models of human airways.   Dr. Marshall left academia in 2016 and is now working as a Science Advisor for the Humane Society of the United States (HSUS). Her overarching goal in this post is the encouragement of animal replacement in biomedical research, and she is specifically involved in identifying alternatives to animal models for investigating human disease mechanisms and treatments. It is Dr. Marshall’s view that the availability of reliable, robust human models is vitally important since they provide a useful and much-needed testing platform for novel drug candidates whilst removing the requirement for animal testing.