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🧪 What is ACLF and why does it matter? In this in-depth interview, Professor Joan Clària, Senior Consultant in Clinical Biochemistry at Hospital Clínic-IDIBAPS, Professor of Biomedicine at the University of Barcelona, and Head of Translational Operations at EF CLIF, shares his expert perspective on Acute-on-Chronic Liver Failure (ACLF) and the pivotal role of systemic inflammation in its pathogenesis. He explains how systemic inflammation drives ACLF, leading to immune dysfunction and organ failure. Drawing on years of translational research, he outlines his group’s key discoveries, scientific challenges, and what’s next for innovation in ACLF research. 🔬 Topics covered include: What is ACLF? Why is systemic inflammation so intense in ACLF? Can you describe your research in ACLF? How does inflammation lead to organ failure? Infection and immune dysfunction in ACLF? What is your group’s main expertise in ACLF? What are the key findings from your research? Your key translational research in ACLF? What are the main challenges in ACLF research? What is next for translational research in ACLF? #ACLF #LiverFailure #JoanClaria #Inflammation #ImmuneDysfunction #TranslationalResearch #EFCLIF #LiverDisease #Hepatology #BiomedicalResearch #OrganFailure #PatientCare #LiverHealth