Frontline Treatments Metastatic Colon Cancer скачать в хорошем качестве

Frontline Treatments Metastatic Colon Cancer

The most important base medication is called 5FU (Fluorouracil), a drug that can be taken by either an IV drip or pill form. Two additional chemotherapy medications are later added; oxaliplatin and irinotecan. Although Oxaliplatin and Irinotecan are beneficial to patients, they may introduce symptoms of neuropathy, hair loss, diarrhea, and nausea. Avastin (bevacizumab) is usually the third and last medication added to a treatment regimen for colorectal cancer patients, and works by cutting off blood supply to cancerous tumors. In cases depending on specific genetics, a fourth medication may be added if your doctor thinks it would benefit your treatment. More Videos: https://ruesch.georgetown.edu/rueschr... Transcript: You're about to set out on treatment for colorectal cancer, metastatic stage IV colon cancer. And you may have read ... there's a bunch of different medicines out there ... Why is your doctor picking these specific medicines to give to you? And I just wanna walk you through the basics of these medicines. The most important base medicine, if you will, is a drug called 5FU. It comes in two flavors. It comes in an IV form, which is given to you to-go through an infusion pump that you take home for two days and then either come back to have it disconnected or sometimes a nurse will come to your house and disconnect it. That pump 5FU also comes in a pill form called Xeloda or Capecitabine and those two drugs are equivalent. And some people don't like pills, some people like the pump, and vice versa. We tend to use more pills around here than pump, but that's between you and your doc to decide. They're the same, right? We add to that a chemo medicine; and there are two chemo medicines. One is called oxaliplatin, one is called irinotecan. They add benefit but they also add side effects. Oxaliplatin is known for neuropathy, pins and needle feeling of cold side effect. Irinotecan, a little more hair loss, a little bit more diarrhea associated with it. Both have some nausea associated with it, but are pretty well tolerated. And then we usually add a third drug, a biologic. The most common drug that's added in this space is called Avastin or bevacizumab. And it works by choking off the blood supply to the cancers. Some patients are eligible for a drug called or Cetuximab or panitumumab but they have to have a particular gene test that are positive, and believe it or not, their tumors needs to be on the left side. So usually we use the three-drug cocktail of 5FU, Ox or Iri, and a biologic and set out. Some of us push some patients even harder by adding a fourth drug to the mix but that's a discussion between you and your doc. And sometimes we actually back down and only use two drugs right from the beginning. Again, a discussion between you and your doc. So, generally speaking, three-drug regimens going forward; that has a pretty high probability of shrinking your cancer. And, going forward, whether you'll need more drugs, when and how, will be between you and your doc.