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Prof Mehanna talks to ecancertv at ECC 2015 about part of the PET-NECK randomized controlled study that examined the quality of life and functional differences of head and neck cancer patients receiving chemoradiotherapy who were randomized to neck dissection or watchful waiting with neck dissection only if a PET-CT scan showed the need. In the interview he discusses whether planned neck dissection is really needed for all patients or if watching waiting can suffice. He also recommends that clinicians know the HPV status of their patients as this can affect their quality of life during treatment and need for additional support. ecancer's filming at ECC 2015 has been kindly supported by Amgen through the ECMS Foundation. ecancer is editorially independent and there is no influence over content.