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Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this high-yield neuropathology lecture, Professor Zach Murphy breaks down the major Stroke Syndromes, focusing on how occlusions in specific cerebral arteries produce distinct clinical presentations. This lecture will help you localize lesions based on neurologic deficits and understand the vascular anatomy of the brain. We begin by reviewing the Circle of Willis and major cerebral arteries, then systematically cover the classic syndromes associated with: • Middle Cerebral Artery (MCA): Contralateral face/arm weakness and sensory loss, aphasia (if dominant hemisphere), or hemineglect (if non-dominant) • Anterior Cerebral Artery (ACA): Contralateral leg weakness and sensory loss, urinary incontinence, and possible abulia • Internal Carotid Artery (ICA): Often causes MCA-like deficits with possible retinal ischemia (amaurosis fugax) and border zone (watershed) infarcts • Posterior Cerebral Artery (PCA): Contralateral homonymous hemianopia, visual agnosia, and memory disturbances if medial temporal lobe is involved • Vertebrobasilar Arteries: Brainstem and cerebellar signs—dysarthria, dysphagia, vertigo, ataxia, cranial nerve deficits, and in severe cases, locked-in syndrome Throughout the lecture, we connect vascular territories to functional brain regions and explain how to interpret patterns of motor, sensory, visual, language, and cognitive impairments in both anterior and posterior circulation strokes. Enjoy the lecture and support us below! Table of Contents: 0:00 Classroom 0:42 MCA Syndrome 19:06 ACA Syndrome 27:31 MCA / ACA Watershed Zones 29:51 ICA Syndrome 33:48 MCA / PCA Watershed Zones 37:14 Anterior Circulation vs Posterior Circulation Strokes 37:57 PCA Syndrome 40:01 Midbrain Lesions: Weber, Claude, Benedikt Syndrome 44:21 Basilar Artery Syndromes 1:01:22 Vertebral Artery Syndromes 1:16:15 Comment, Like, SUBSCRIBE! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #strokes #CVA