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The pancreas has both exocrine and endocrine functions. The pancreatic islet cell types include alpha cells, which produce glucagon; beta cells, which produce insulin; delta cells, which produce somatostatin; and PP cells, which produce pancreatic polypeptide. Insulin and glucagon are involved in the regulation of glucose metabolism. Insulin is produced by the beta cells in response to high blood glucose levels. It enhances glucose uptake and utilization by target cells, as well as the storage of excess glucose for later use. Dysfunction of the production of insulin or target cell resistance to the effects of insulin causes diabetes mellitus, a disorder characterized by high blood glucose levels. The hormone glucagon is produced and secreted by the alpha cells of the pancreas in response to low blood glucose levels. Glucagon stimulates mechanisms that increase blood glucose levels, such as the catabolism of glycogen into glucose. 00:00 The Endocrine Pancreas 00:37 Cells and secretions of the pancreatic islets 02:03 Regulation of blood glucose levels by insulin and glucagon 02:52 Glucagon 04:11 Insulin 06:53 Disorders of the… 12:30 Chapter review Attribution: OpenStax, Anatomy & Physiology Book https://openstax.org/books/anatomy-an...