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Panosteitis, commonly called Pano, a disease primarily affecting young growing large breed dogs, is characterized by inflammation within the bones, most often the legs. The most common symptom is pain and lameness, often one or multiple legs, that seems to wax and wane, with symptoms lasting from 1-6 months. Pano is considered self-limiting, which means it often spontaneously heals, but dogs often require treatment with anti-inflammatory drugs to remain comfortable during the active phase of the problem. X-rays may or may not be necessary but always consult a qualified veterinarian to give a good medical history and have the doctor perform a complete physical examination before diagnosis and/or treatment!