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In this session at IFSO Integrated Health, Dr. Christina, exercise physiologist and strength training specialist from Brazil, highlights strategies to preserve lean muscle mass during and after bariatric surgery and pharmacological obesity treatments. Key points: Muscle and lean mass loss: Obesity medications and bariatric surgery can lead to significant lean mass loss, which can impact metabolism, frailty, and increase risk of weight regain. Accurate measurement is challenging; DXA scans may overestimate muscle loss. Gold standards include MRI, ultrasound, and CT scans. Focus on muscle health: Prioritize strength, function, and quality of life over absolute muscle mass. Muscle health supports independence, mobility, and long-term success after weight loss. Effective strategies for hypertrophy and strength: Load: High or low load performed near muscle failure can stimulate hypertrophy. Training volume: Multiple sets and sessions per week provide dose-response benefits. Volume load can be equated across different set-repetition schemes. Time under tension: Controlled, slow movements recruit more muscle fibers and maximize hypertrophy. Exercise variety and planning: Multi-angle exercises and periodized training prevent stagnation and improve neuromuscular adaptation. Combined aerobic + strength training: Mitigates side effects of obesity medications like increased heart rate, improves cardiovascular fitness, and preserves joints. Lifestyle integration: Exercise and nutrition (adequate protein intake) are crucial alongside medications or surgery. Focus on function and strength, not just weight loss. Research gaps: There is a need for high-quality RCTs with clear terminology, standardized protocols, and proper measurement of muscle health outcomes in post-bariatric and pharmacotherapy patients. Conclusion: Long-term success after bariatric surgery or obesity medications is not just about weight loss. Preserving lean mass, maintaining strength, and enhancing function are the keys to better health, independence, and quality of life. Visit https://www.ifso.com/ for more information.