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CLINICAL - ILIOTIBIAL SYNDROME Iliotibial band syndrome (ITBS) is a common knee injury that usually presents with pain and/or tenderness on palpation of the lateral aspect of the knee, superior to the joint line and inferior to the lateral femoral epicondyle.[1]. It is considered a non-traumatic overuse injury and is often concomitant with underlying weakness of hip abductor muscles.[2] Overuse is thought to be caused by repetitive knee flexion and extension movements frequently seen in cyclists and runners [1][3]. This repetitive motion causes excessive friction between the lateral femoral epicondyle and the iliotibial tract. Studies have described an ‘impingement zone’ occurring at, or slightly below, 30° of knee flexion during foot strike and the early stance phase of running. During this impingement period in the running cycle, eccentric contraction of the tensor fascia latae muscle and of the gluteus maximus causes the leg to decelerate, generating tension in the iliotibial band.[4] Clinically Relevant Anatomy Itbs.png The iliotibial tract is a thick band of fascia that runs on the lateral side of the thigh from the iliac crest and inserts at the knee.[5] It is composed of dense fibrous connective tissue that appears from the m. tensor fasciae latae and m. gluteus maximus. It descends along the lateral aspect of the thigh, between the layers of the superficial fascia, and inserts onto the lateral tibial plateau at a projection known as Gerdy’s tubercle[2]. In its distal portion the iliotibial tract covers the lateral femoral epicondyle and gives an expansion to the lateral border of the patella. While the iliotibial band does not have any boney attachments as it courses between the Gerdy tubercle and the lateral femoral epicondyle, this absence of attachment allows it to move anteriorly and posteriorly with knee flexion and extension. Histologic and dissection study of the iliotibial band at the lateral femoral epicondyle and gluteus maximus and fascia lata suggest a mechanosensory role acting proximally on the anterolateral knee. Figure [1] This mechanosensory role may affect the interpretation of the ligament versus tendon function of the ITB from hip to lateral femoral epicondyle The iliotibial tract, also known as the iliotibial band, is a thick strip of connective tissue connecting several muscles in the lateral thigh. It plays an important role in the movement of the thigh by connecting hip muscles to the tibia of the lower leg. Located on the lateral edge of the fascia lata, the iliotibial tract forms a wide sheath of fibrous connective tissue that surrounds the lateral thigh. It arises at its proximal end from the tendons of the tensor fasciae latae and gluteus maximus muscles. From its origin, the iliotibial tract travels along the lateral side of the thigh and across the knee joint, inserting on the lateral epicondyle of the tibia