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A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology). Low-grade fibromyxoid sarcoma (LGFMS; aka Evans tumor) is a very unusual low grade sarcoma with fibrous and myxoid stroma. It has several important clinical and histologic features that I discuss in detail in this video. Also discussed is hyalinizing spindle cell tumor with giant rosette, which is a unique morphologic subtype of LGFMS (click here: 27:55). Note: despite the similar sound of the name, this tumor is unrelated to myxofibrosarcoma. Additional relevant videos: FIBROmyxo vs MYXOfibro Sarcoma Made Simple: https://kikoxp.com/posts/3705 Low grade fibromyxoid sarcoma (LGFMS): https://kikoxp.com/posts/4189 Myxofibrosarcoma (full video): https://kikoxp.com/posts/4190 Perineurioma (vs LGFMS at 14:50): https://kikoxp.com/posts/3694 Additional suggested reading: Evans HL. Low-grade fibromyxoid sarcoma: a clinicopathologic study of 33 cases with long-term follow-up.: https://www.ncbi.nlm.nih.gov/pubmed/2... Thway K, Fisher C, Debiec-Rychter M, Calonje E. Claudin-1 is expressed in perineurioma-like low-grade fibromyxoid sarcoma. https://www.ncbi.nlm.nih.gov/pubmed/1... Billings SD, Giblen G, Fanburg-Smith JC. Superficial low-grade fibromyxoid sarcoma (Evans tumor): a clinicopathologic analysis of 19 cases with a unique observation in the pediatric population: https://www.ncbi.nlm.nih.gov/pubmed/1... Sedrak MP, Parker DC, Gardner JM. Low-grade fibromyxoid sarcoma with nuclear pleomorphism arising in the subcutis of a child. https://www.ncbi.nlm.nih.gov/pubmed/2... Doyle LA, Möller E, Dal Cin P, Fletcher CD, Mertens F, Hornick JL. MUC4 is a highly sensitive and specific marker for low-grade fibromyxoid sarcoma. https://www.ncbi.nlm.nih.gov/pubmed/2... Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation. Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos. Follow me on: Snapchat: JMGardnerMD Twitter: @JMGardnerMD Instagram: @JMGardnerMD Kiko: https://kikoxp.com/profile/jerad_gard... Facebook: / jmgardnermd