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During the 111th session of the Global NMR Discussion Meetings held on November 18th, 2025, via Zoom, Dr. Frederique Pourpoint from the University of Lille, France, gave a talk on the topic "Stability of MOFs in the presence of water by solid-state NMR". The recording serves as a tutorial. Find out more about Dr Frederique Pourpoint's research : https://uccs-old.univ-lille.fr/index.... Abstract: The stability of MOFs in the presence of water is a key factor for their performance in numerous applications. We demonstrated that quadrupolar nuclei like 17O and 91Zr offer unique insight into the inorganic cluster of MOFs such as Zirconium-based UiO-66, despite the low natural abundance of 17O and the ultra wide line of 91Zr spectra. Content of this video : 00:00 - 05:09 Introducing ssNMR for MOFs study 05:10 - 10:06 Preparation of UiO-66 10:07 - 12:07 Dehydration of the sample varying the temperature 12:08 - 19:01 Study of the metallic cluster 19:02 - 24:46 Studies under steam treatment 24:47 - 35:46 17O for studying MOFs 35:47 - 43:36 Q&A Current organizers: Adrian Draney (Creighton Uni.) Amrit Venkatesh (University of Virginia) Asif Equbal (New York Uni., Abu Dhabi) Charlotte Bocquelet (HMRLab, CRMN Lyon) Diganta Sarkar (Alberta Uni.) Julie Buhl (Uni. JKU Linz) Marcel Levien (Emsley Lab, EPFL) Mengshan Ye (Miller Institute, UC Berkeley) Mouzhe Xie (Arizona State Uni.) Nikita Rao (Indian Institute of Science, Bangalore) Nesreen Elathram (Debelouchina Lab, UCSD) Tamali Nag (Uni. of Lille/Grenoble)