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Ever wondered why some patients have high prolactin levels but show no symptoms? This video dives into Macroprolactinemia, a frequently overlooked cause of asymptomatic hyperprolactinemia. Learn how high molecular weight prolactin can lead to misleading lab results, why it usually doesn’t cause clinical symptoms, and how to accurately diagnose and manage it. We’ll cover: • What macroprolactin is and how it forms • Why routine prolactin tests can be misleading • Laboratory tests to distinguish macroprolactinemia from true hyperprolactinemia • Clinical implications and avoiding unnecessary treatment Perfect for medical students, residents, and clinicians wanting high-yield insights into endocrine diagnostics. Join the StudyNeuro community for more neuroscience and endocrinology pearls: YouTube: @StudyNeuro | Facebook: @StudyNeuro | TikTok: @studyneuroofficial | Instagram: @studyneuroofficial | X: @StudyNeuro2025 🔔 Like, comment, share, and subscribe for more high-yield neuroscience content! Hashtags: #macroprolactinemia, #hyperprolactinemia, #endocrinology, #medicaleducation, #neuroscience, #pituitarydisorders, #prolactin, #clinicalpearls, #studyneuro, #medicalstudents, #anterior and posterior pituitary gland, #anterior and posterior pituitary gland difference, #anterior and posterior pituitary hormones, #anterior and posterior pituitary gland functions, #anterior and posterior pituitary gland histology, #anterior pituitary gland functions, #anterior pituitary gland hormones, #anterior pituitary gland location, #anterior pituitary gland structures, #posterior pituitary gland functions, #posterior pituitary gland hormones, #posterior pituitary gland location, #posterior pituitary gland structures, #anterior pituitary, #posterior pituitary, #pituitary gland hormones, #pituitary anatomy and physiology, #hypothalamic-pituitary axis, #endocrine system, #pituitary cell types, #clinical relevance pituitary, #pituitary tumors, #studyneuro #pituitarygland #anteriorpituitary #posteriorpituitary #endocrinology #neuroscience #medicaleducation #hormones #hypothalamus #clinicalneuroscience Keywords: Macroprolactinemia, asymptomatic hyperprolactinemia, high prolactin no symptoms, prolactin IgG complex, prolactin lab artifact, endocrine disorders, pituitary prolactin, prolactin diagnosis, hyperprolactinemia causes, medical education, StudyNeuro, prolactin levels, PEG precipitation test, prolactin immunoassay, anterior and posterior pituitary gland, anterior and posterior pituitary gland difference, anterior and posterior pituitary hormones, anterior and posterior pituitary gland functions, anterior and posterior pituitary gland histology, anterior pituitary gland functions, anterior pituitary gland hormones, anterior pituitary gland location, anterior pituitary gland structures, posterior pituitary gland functions, posterior pituitary gland hormones, posterior pituitary gland location, posterior pituitary gland structures, anterior pituitary, posterior pituitary, pituitary gland hormones, pituitary anatomy and physiology, hypothalamic-pituitary axis, endocrine system, pituitary cell types, clinical relevance pituitary, pituitary tumors