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These videos explore how endometriosis, affecting about one million women in Canada, can cause deep dyspareunia due to inflammation and increased nerve cells in the pelvic region, and also discuss central sensitization—a condition where the central nervous system amplifies pain signals, which can exacerbate pain during sex even without direct contact with endometrial lesions. Read the full transcript here: https://cansagevideos.com/cansage-202... Presented By: Dr. Natasha L. Orr Dr. Heather Noga Dr. Mohamed A. Bedaiwy Dr. Christina Williams Dr. Catherine Allaire Dr. Paul J. Yong Affiliations: BC Women’s Center for Pelvic Pain and Endometriosis Women’s Health Research Institute University of British Columbia The video series on endometriosis addresses the significant impact of this condition on sexual health, particularly focusing on deep dyspareunia—a common symptom for those afflicted. Endometriosis, often located in the posterior cul-de-sac, leads to heightened levels of estrogen and an increase in nerve cells, contributing to pelvic inflammation and pain. This anatomical and physiological setup can make deep vaginal penetration painful, affecting approximately 50% of those with the condition in Canada. Furthermore, the series delves into the concept of central sensitization, a critical but less direct effect of endometriosis on pain perception. Central sensitization occurs when the central nervous system, including the brain and spinal cord, becomes overly sensitized, leading to an exaggerated response to pain stimuli. This can make even light touches feel painful and is not limited to areas directly affected by endometriosis, thus complicating the experience of sexual pain. It highlights that while surgical or pharmaceutical treatments might alleviate endometriosis, they may not effectively address pain derived from central sensitization. Instead, a multifaceted approach including physiotherapy, psychological interventions, and specific pain management strategies may be required to manage this complex symptomatology effectively. By explaining both the direct and indirect impacts of endometriosis on painful sex, the video series underscores the importance of tailored treatments and the necessity for individuals to seek professional healthcare advice for managing their condition and improving their quality of life.