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This keynote lecture was presented at the 32nd International Congress of Antimicrobial Chemotherapy (ICC) in Perth, Australia. Dr Jennifer Coetzee is a Principal Pathologist at Ampath Laboratories, South Africa whose research interests include the epidemiology of invasive fungal infections. In this lecture, Dr Coetzee shares her experience of Aspergillosis in critical care settings including the challenges in making a diagnosis of invasive Aspergillus, current treatments and azole resistance in Aspergillus. Subscribe to ISAC's YouTube Channel to watch other excellent plenary / keynote lectures as they are uploaded. Visit www.ISAC.world for more information about ISAC and how to join. Disclaimer The webinars / lectures provided by the International Society of Antimicrobial Chemotherapy (ISAC) are for informational purposes only. No material contained herein is intended to be a substitute for professional medical advice, diagnosis, treatment or national / local guidelines. The opinions expressed in a webinar are those of the author(s) only and may not necessarily represent the views of ISAC. Where links are provided to other sites and resources of third parties, these links are provided for your information only. ISAC neither endorses not accepts responsibility for the contents of those sites or resources.