The Powerhouses of Longevity: Mitochondrial Optimization with Dr. Elizabeth Yurth скачать в хорошем качестве

The Powerhouses of Longevity: Mitochondrial Optimization with Dr. Elizabeth Yurth

Mitochondrial health is the foundation of longevity, energy, and resilience—and it’s far more than “the powerhouse of the cell.” In this episode of The Dr. Jones Optimization Academy, Dr. Greg Jones welcomes Dr. Elizabeth Yurth (Boulder Longevity Institute) to explain how mitochondrial optimization impacts hormones, inflammation, brain function, and healthy aging. You’ll learn how declining mitochondrial health drives fatigue, brain fog, poor recovery, and chronic disease—and what you can do to reverse course. We cover the essentials: mitochondrial roles in ATP production, calcium balance, apoptosis, steroidogenesis, and immune signaling; how oxidative stress, toxins, infections, circadian disruption, and poor sleep impair function; and the most useful labs and real-world proxies (VO₂, lactate, organic acids, oxidative stress markers, Prodrome Scan, CGM patterns). Dr. Yurth details lifestyle levers—resistance training, HIIT, Zone 2, fasting/carb cycling, sauna + cold exposure (timed correctly), red light, and sleep optimization—then moves into targeted tools for mitochondrial optimization: creatine, ketones, CoQ10, alpha-lipoic acid, 1-MNA/apigenin for NAD support, plus when to be cautious with chronic NMN/NR use. We also explore mitochondrial peptides and emerging therapies—SS-31 (elamipretide), MOTS-c, Humanin, 5-amino-1MQ, and what’s on the horizon with exercise mimetics and uncouplers—along with practical cycling, safety notes, and who should avoid certain compounds. If you’re seeking a clear roadmap to improve energy, recovery, and long-term health, this masterclass on mitochondrial health gives you evidence-informed, actionable steps. 📌 Guest – Dr. Elizabeth Yurth Boulder Longevity Institute: https://boulderlongevity.com/ BLI Academy (Clinician Education): https://bli.academy IG: @dryurth 📌 Connect with Dr. Greg Jones IG: @doctorjones_doctorjones Become a patient: https://enovativewellness.com/ 📣 Subscribe for more on hypertension, longevity, and root-cause cardiometabolic health: YouTube:    / @drgregjonesnmd   Spotify: https://open.spotify.com/show/2QrMGwC... 🔗 Want to learn more? Check out these resources: NIH – “Mitochondria” (NCBI Bookshelf): https://www.ncbi.nlm.nih.gov/books/NB... National Institute on Aging – Mitochondria & Aging: https://www.nia.nih.gov/health/ Harvard Medical School – VO₂ max & longevity insights: https://www.health.harvard.edu/ Review: PGC-1α & mitochondrial biogenesis (PubMed): https://pubmed.ncbi.nlm.nih.gov/18487... 🔬 Timestamps: 00:00 – Intro: mitochondria & longevity overview 00:57 – Dr. Yurth’s recent work in cellular medicine 04:34 – Why mitochondria drive energy and lifespan 07:05 – The mitochondria–hormone production connection 08:20 – Mitochondrial dysfunction: root cause of chronic disease 11:24 – Oxidative stress, ROS, and “inflammaging” 17:33 – Signs & symptoms of mitochondrial dysfunction 24:31 – Environmental stressors (toxins, stress, diet, sleep) 31:31 – Can we test mitochondria? Labs & biomarkers 39:00 – Lifestyle levers: fasting, exercise, red light 45:15 – Supplements: CoQ10, 1-MNA, creatine, NAD strategy 48:39 – Ketones & creatine as performance enhancers 55:33 – Peptides: SS-31, Humanin, MOTS-c, 5-amino-1MQ 01:01:56 – How SS-31 repairs membranes & boosts ATP 01:09:53 – What’s next: uncouplers & new peptides 01:14:48 – Dr. Yurth’s #1 longevity lesson 01:18:08 – Where to learn more (BLI & Academy) #MitochondrialHealth #Longevity #CellularMedicine #Peptides #Energy #Recovery Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations.