60-Second Journal Club: Liraglutide for Children with Obesity скачать в хорошем качестве

60-Second Journal Club: Liraglutide for Children with Obesity

Obesity is a chronic, relapsing, and progressive disease that necessitates appropriate management strategies endorsed by multiple guidelines. No medications are currently approved for the treatment of nonmonogenic, nonsyndromic #obesity in children younger than 12 years of age. Although the use of liraglutide has been shown to induce weight loss in adults and adolescents with obesity, its safety and efficacy have not been established in children. The SCALE Kids trial, summarized here by NEJM Editorial Fellow Harleen Marwah, MD, assessed the efficacy and safety of liraglutide, as compared with placebo, as an adjunct treatment to lifestyle interventions, for the treatment of obesity in children 6 to 12 years of age. Full trial results: https://nej.md/3MBP1uc #pediatrics #endocrinology #clinicaltrials #nejm