Total Synthesis of Psathyrin A (Dai, 2025) скачать в хорошем качестве

Total Synthesis of Psathyrin A (Dai, 2025)

An organic chemistry minilecture on the 'Total Synthesis of (−)-Psathyrin A Enabled by Radical Cyclization' by Weizhao Zhao, Reem Al-Ahmad, and Mingji Dai*. It features an Asymmetric Conjugate Addition, a Conia-Ene cyclization and a Metal-Catalyzed Hydrogen Atom Transfer reaction. SUPPORT THE CHANNEL ON PATREON:   / simplifyingsynthesis   NMR Spectroscopy in music: J. New Music Res. 2021, 50:5, 487-501 Socials:   / simplifyingsynthesis     / simplifyingsyn1     / simplifyingsynthesis   References: J. Am. Chem. Soc. 2025, 147, 36, 32365–32369 (This work) J. Nat. Prod. 2020, 83, 1725−1729 (Psathyrin A Isolation) Eur J Org Chem, 2012, 27, 5301–5306 (Asymmetric Conjugate Addition) J. Am. Chem. Soc. 2014, 136, 4, 1304–1307 (MHAT coupling) J. Am. Chem. Soc. 2017, 139, 6, 2484–2503 (MHAT coupling) Tetrahedron Lett. 1994, 35, 8409−8412 (TBAF catalyzed silylation)