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Alcohol use can be associated with various physical and emotional issues. The negative ramifications associated with alcohol use are related to the amount of alcohol that a person uses, not to the type of alcohol consumed. There are two main types of alcohol abuse disorders: binge drinking and alcoholism. This video defines both of these disorders as well as the mechanism of action and potential treatments. This video was made by McMaster Demystifying Medicine students Sarah Cash, Eric Chu, Masha Gholiof and Parsa Hosseini-jahromi. Copyright McMaster University 2020 References: 1. Close, L., Thomas, S., Kelley, R., Stein, S. and Osbourne, N., 2019. The Distinction Between Binge Drinking & Alcoholism. Sunrise House. Available at: https://sunrisehouse.com/stop-drinkin... 2. Ezquer, F., Morales, P., Quintanilla, M. E., Santapau, D., Lespay-Rebolledo, C., Ezquer, M., Herrera-Marschitz, M., & Israel, Y. Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking. Sci. Rep. 8 (2018). 3. Hardey, S., Thomas, S., Stein, S., Kelley, R. and Ackermann, K., 2019. Binge Drinking: When Does It Become A Problem?. American Addiction Centers. Available at: https://americanaddictioncenters.org/... 4. Morse, R., 1992. The Definition of Alcoholism. JAMA, 268(8), p.1012. 5. Tateno, M. & Saito, T. Biological Studies on Alcohol-Induced Neuronal Damage. Psychiatry Investig 5, 21–27 (2008). 6. Sullivan, E. V. & Zahr, N. M. Commentary on "Increased MCP-1 and Microglia in Various regions of Human Alcoholic Brain". Experimental Neurology 213, 10–17 (2008).