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In this podcast episode, experts Angela Weyand and Guy Young discuss their experience using hemostatic rebalancing agents for prophylaxis in patients diagnosed with hemophilia. Three rebalancing agents have now been approved, including concizumab, fitusiran, and marstacimab. These new rebalancing agents target the body's natural anticoagulants and provide individualized, convenient options for patients older than 12 years of age.This podcast explores similarities and differences between the rebalancing agents, such as dosing, necessary lab testing, and safety profiles, that are important to discuss with patients and their caregivers. Presenters: Angela Weyand, MD Associate Professor, Pediatric Hematology Oncology Co-Director, Combined Hematology/Gynecology Program Pediatric Medical Director, Hemophilia Treatment Center University of Michigan Medical School Ann Arbor, Michigan Guy Young, MD Director, Hemostasis and Thrombosis Center Director, Clinical Coagulation Laboratory Cancer and Blood Disease Institute Children's Hospital Los Angeles Professor of Pediatrics Division of Hematology/Oncology Department of Pediatrics University of Southern California Keck School of Medicine Los Angeles, California Get access to all of our new podcasts by subscribing to the CCO Neuroscience Podcast on Apple Podcasts, YouTube Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com (https://pcm.adswizz.com) for information about our collection and use of personal data for advertising.