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Shedding light on tumor cells

A film partly shot at the Sainte Anne Hospital. How can a neurosurgeon be sure that he removed the totality of the tumour from his patient's brain, while preserving healthy neighbouring tissues ? To help the practitioner, researchers and physicians collaborate to develop a camera able to reliably distinguish healthy cells from diseased cells. To do this, it will analyse the fluroescence naturally emitted by the tissue, rich in information, and compare the result with a database before giving its final result: healthy tissue or tumour tissue. To feed this database, researchers come to, among others, Synchrotron SOLEIL, on the DISCO beamline to establish the characeristics of the different types of cells in the ultraviolet. Acknowledgments: ➢ Institut National de la Santé et de la Recherche Médicale, l'AAP (2012-2014-2016/ MEVO & IMOP) - PLAN CANCER ➢ Agence Nationale pour la Recherche au titre du programme « Investissements d’avenir » - FLI ➢ Mission pour l’interdisciplinarité « l’instrumentation aux limites » - CNRS ➢ Plateforme « PIMPA », Paris Sud ➢ Université Paris Diderot, Sorbonne Paris Cité ➢ Laboratoire IMNC-UMR 8165-CNRS/IN2P3, Université Paris-Saclay Thanks to Pr. Bertrand Devaux who has supported this project since the beginning, and Pascale Varlet, neuropathologist.