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Read KM curves - Pearls and Details

Using examples from the cancer literature, the video explains how to read Kaplan Meier curves. It gives background for prostate cancer and choroid plexus carcinoma to explain the curves: Determine median survival and 10 year survival from the curve. Understand the check marks, the stair shape of PFS curves, with sharp and soft steps, and the final drop of KM curves. It uses the style of slide decks and Journal clubs to explain. Previous videos of this series included: Kaplan Meier Curve - What is that ?    • PFS progression free survival explained   PFS - Progression Free Survival explained    • Видео   These videos are made for cancer drug development researchers. Patients are welcome to listen, but there are better videos for you. Topics covered include: prostate cancer, choroid plexus carcinoma, choroid plexus papilloma, Kaplan Meier Curves, OS = overall survival , EFS = event free survival, the stair-shape of EFS curves, the final drop of KM curves, FDA approval, NCCN guidelines, and other topics. 00:00 - Introduction 01:36 - Choroid Plexus Tumors 03:55 - EFS curves, mEFS, 10Year EFS 06:55 - Carboplatin was better that cyclophosphamide 07:07 - Prostate Cancer Overview 08:00- Fizazi 2019: Darolutamide New England Journal of Medicine 13:00 - EFS curves stairs and steps 16:00 - OS curves - only one type of steps 17:00 - Summary