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Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this embryology lecture, Professor Zach Murphy walks you through the development of the placenta, a vital structure that supports fetal growth and survival throughout pregnancy. This lecture outlines how maternal and fetal tissues come together to form a functional fetomaternal interface that facilitates gas exchange, nutrient delivery, waste removal, hormone production, and immune protection. We begin with the differentiation of the trophoblast into two key layers: the cytotrophoblast and the syncytiotrophoblast, explaining how these layers contribute to implantation and invasion of the maternal endometrium. Zach details the formation of primary, secondary, and tertiary chorionic villi, which become the structural and functional units of the placenta. The lecture then explores the contributions of the extraembryonic mesoderm, the formation of the chorionic plate, and how umbilical vessels develop and establish connections with the embryonic circulatory system. We also discuss the decidua basalis, placental barrier, and how the maternal and fetal circulations remain separate yet intimately linked. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #PlacentaDevelopment #Embryology