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Novo Nordisk just said something that could shape the future of GLP-1 pricing. On its latest earnings call, CEO Mike Doustdar made a clear statement: price reductions are an investment in capturing more patients. That single line may signal a major shift in how obesity medications are priced, positioned, and expanded in the United States. In this episode of The Downsized, Christopher Durham breaks down Novo Nordisk’s full year 2025 earnings results and explains what the numbers really mean for patients who are using GLP-1s to treat the disease of obesity. Sales are still growing, but the explosive surge phase appears to be moderating. Pricing pressure is real. Competition with Eli Lilly is intensifying. And Novo is making deliberate decisions about access, rebates, and market share. Christopher walks through: • Novo’s 2025 sales and profit growth • The strategic focus on obesity and diabetes • U.S. pricing headwinds and why revenue is declining domestically • Early prescription data for oral Wegovy • The pipeline, including CagriSema and next-generation combinations • Analyst concerns about competition, guidance, and long-term durability Between Christopher and Laraine, they have lost more than 150 pounds since beginning their GLP-1 adventure in September 2023. They have paid out of pocket, dealt with shortages, and experienced the system firsthand. This analysis is not abstract market commentary. It is about the infrastructure behind real patient care. As always, this channel works directly from earnings transcripts, investor presentations, and regulatory filings to translate complex financial language into plain English for people navigating obesity treatment. If you are new to the channel, welcome. The Downsized publishes daily content covering GLP-1 research, policy, pricing, pipeline developments, and real patient experiences. If Novo truly views price reductions as an investment, the next year could reshape GLP-1 access in ways that matter deeply to patients. +++++++++++++++++++++++++++++++++++++++ Get your Hume BodyPod today and use our exclusive Downsized code for up to 50% total savings! 👉 Use our Code: THEDOWNSIZED Link to purchase: https://humehealth.com//discount/THED... Start your weight loss journey today! We use Mochi Health: https://app.joinmochi.com/eligibility... Use Laraine’s code for $40 off: QIYGO8. Me Again Iphone GLP-1 App: https://apps.apple.com/us/app/meagain... AMAZON GLP-1 Companion Product Store: https://www.amazon.com/shop/downsized As an Amazon Associate, I earn from qualifying purchases. DOWNSIZED LINKS Website: https://thedownsized.org Be our guest on The Downsized Dish: apply at https://thedownsized.org/downsized-dish/ Https://Thedownsized.Org/ Book The Downsized At Sea Cruise 2026: Https://Thedownsized.Org/Downsized-At... FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ +++++++++++++++++++++++++++++++++++++++ 00:00 “Price Cuts Are an Investment” Novo’s CEO Escalates GLP-1 Battle 00:19 Novo Nordisk's Earnings Call Breakdown 00:51 Welcome to The Downsized 01:18 Personal Weight Loss Journey 01:39 Novo's Strategic Focus on Obesity 02:11 Sales Growth and Market Maturity 03:17 Pricing Pressure and Competition 06:35 Pipeline and Product Launches 10:59 Analysts' Concerns and Questions 15:52 Strategic Pricing Decisions 16:38 Future Market Dynamics 21:44 Conclusion and Viewer Engagement