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This clip from NEI's Stahl's Essential Videos discusses how dopamine neurons can be regulated quite differently depending upon which dopamine receptors are present. See more essentials of psychopharmacology from Dr. Stahl and NEI at https://nei.global/epvideos The neurotransmitter dopamine (DA) can be either excitatory or inhibitory, depending upon which dopamine receptor subtype it binds. Currently, dopamine receptors are divided into two groups. The first group is the D1-like receptors, including both D1 and D5 receptors. D1-like receptors are excitatory, and positively linked to adenylate cyclase. The second group is the D2-like receptors, including D2, D3, and D4 receptors. D2-like receptors are inhibitory and negatively linked to adenylate cyclase. All five dopamine receptors can be located postsynaptically, but both D2 and D3 receptors can also be located presynaptically where, due to their inhibitory actions, they act as autoreceptors to inhibit further dopamine release. Dopamine neurons can be regulated quite differently depending upon which dopamine receptors are present. 🧠💡 Struggling to grasp complex psychopharmacologic concepts? Unlock the Power of Visual Learning with NEI's Stahl's Essential Videos! These videos are an NEI Membership feature designed to help you master the fundamentals of psychopharmacology! Learn more at https://nei.global/epvideos Start your learning journey by creating a free NEI Guest account here https://nei.global/createaccount Follow us on Facebook: https://nei.global/facebook Follow us on LinkedIn: https://nei.global/linkedin Follow us on X: https://nei.global/twitter Follow us on Instagram: https://nei.global/instagram 🎙 Listen to NEI Podcast: https://nei.global/podcast Copyright © Neuroscience Education Institute. All rights reserved.