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In this session, Dr. L. Rohit Reddy explains scenarios where adjuvant therapy may benefit patients after esophagus surgery. Key points include using adjuvant immunotherapy for residual disease post neo-adjuvant chemo-radiation, as shown in the CheckMate 577 trial, which demonstrated improved disease-free survival in patients with completely resected margins but remaining disease. He clarifies that giving extra chemotherapy after prior neo-adjuvant therapy usually offers no benefit and increases toxicity. For adenocarcinoma, peroperative chemotherapy is preferred, and adjuvant treatment is needed only for T3/T4 or node-positive disease, or R1/R2 resections. He also reviews chemotherapy combinations: paclitaxel + carboplatin for squamous cell carcinoma, and FLOT or CAPEOX for adenocarcinoma, emphasizing patient fitness and tolerance. Dr. Reddy concludes that esophageal cancer management is complex, requiring a team-based approach with surgeons, medical oncologists, and radiation oncologists. Adjuvant therapy is reserved for specific situations, including residual disease where immunotherapy can improve outcomes. Yashoda Hospitals: Pioneering Healthcare Excellence in Hyderabad Yashoda Hospitals is among India's leading healthcare providers, renowned for its advanced medical technology and world-class facilities. Guided by visionary leadership, the Yashoda Group of Hospitals has emerged as a center of excellence in healthcare, delivering top-quality medical care to all segments of society. With cutting-edge equipment, a team of expert doctors, and a commitment to compassionate care, Yashoda Hospitals ensures that patients receive the best possible treatment for all their health needs. For more information on medical treatment, call us at +91-8929967127 Chat with us in WhatsApp with our experts: https://api.whatsapp.com/send?phone=9... Stay Informed with the Latest Health News: Yashoda Hospitals brings you the most recent updates in medical advancements and healthcare. From groundbreaking treatments to expert tips on healthy living, we keep you updated on the latest in the healthcare industry. Always Get an Expert Second Opinion Before deciding on your Treatment/Surgery. Get a free online second opinion: https://www.yashodahospitals.com/free... Check Our Health Info Updates: https://www.yashodahospitals.com/blog/ Connect with Us Online: Website: https://www.yashodahospitals.com/ Like us on Facebook: / yashodahospitals Follow us on Twitter: / yashodahospital Connect on LinkedIn: / yashodahospitals Follow us on Instagram: / yashoda.hospitals #GIFocus #YashodaHospitals #EsophagealCancer #AdjuvantTherapy #Immunotherapy #NeoAdjuvantTherapy #SurgicalOncology #ChemoRadiation #ThoracicSurgery #PatientOutcomes #ComplexSurgery